ENSG00000099977


Homo sapiens

Features
Gene ID: ENSG00000099977
  
Biological name :DDT
  
Synonyms : D-dopachrome tautomerase / DDT / P30046
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q11.23
Gene start: 23971365
Gene end: 23980469
  
Corresponding Affymetrix probe sets: 202929_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384866
Ensembl peptide - ENSP00000385714
Ensembl peptide - ENSP00000409440
Ensembl peptide - ENSP00000399768
Ensembl peptide - ENSP00000215773
Ensembl peptide - ENSP00000381386
NCBI entrez gene - 100037417     See in Manteia.
NCBI entrez gene - 1652     See in Manteia.
OMIM - 602750
RefSeq - NM_001355
RefSeq - NM_001084392
RefSeq Peptide - NP_001077861
RefSeq Peptide - NP_001346
swissprot - Q53Y51
swissprot - H7C342
swissprot - J3KQ18
swissprot - P30046
swissprot - B5MC82
Ensembl - ENSG00000099977
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddtENSDARG00000044751Danio rerio
 DDTENSGALG00000006350Gallus gallus
 DdtENSMUSG00000001666Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDTL / A6NHG4 / D-dopachrome tautomerase likeENSG0000009997482


Protein motifs (from Interpro)
Interpro ID Name
 IPR001398  Macrophage migration inhibitory factor
 IPR014347  Tautomerase/MIF superfamily
 IPR019829  Macrophage migration inhibitory factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010760 negative regulation of macrophage chemotaxis IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IDA
 biological_processGO:0042438 melanin biosynthetic process IEA
 biological_processGO:0050729 positive regulation of inflammatory response IC
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IGI
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004167 dopachrome isomerase activity TAS
 molecular_functionGO:0005126 cytokine receptor binding IDA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0033981 D-dopachrome decarboxylase activity IEA
 molecular_functionGO:0050178 phenylpyruvate tautomerase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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