ENSG00000100209


Homo sapiens

Features
Gene ID: ENSG00000100209
  
Biological name :HSCB
  
Synonyms : HSCB / HscB mitochondrial iron-sulfur cluster cochaperone / Q8IWL3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q12.1
Gene start: 28742031
Gene end: 28757515
  
Corresponding Affymetrix probe sets: 223647_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416679
Ensembl peptide - ENSP00000216027
Ensembl peptide - ENSP00000381914
Ensembl peptide - ENSP00000406284
NCBI entrez gene - 150274     See in Manteia.
OMIM - 608142
RefSeq - XM_017028620
RefSeq - NM_001318314
RefSeq - NM_001318315
RefSeq - NM_001318316
RefSeq - NM_172002
RefSeq - XM_005261359
RefSeq - XM_017028619
RefSeq Peptide - NP_741999
RefSeq Peptide - NP_001305245
RefSeq Peptide - NP_001305244
RefSeq Peptide - NP_001305243
swissprot - F8WBY7
swissprot - Q8IWL3
swissprot - B0QYH2
Ensembl - ENSG00000100209
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-207k7.4ENSDARG00000075416Danio rerio
 HSCBENSGALG00000005706Gallus gallus
 HscbENSMUSG00000043510Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR004640  Co-chaperone Hsc20
 IPR009073  Co-chaperone HscB, C-terminal oligomerisation domain
 IPR036386  HscB, C-terminal domain superfamily
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016226 iron-sulfur cluster assembly IMP
 biological_processGO:0032781 positive regulation of ATPase activity IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0097428 protein maturation by iron-sulfur cluster transfer IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0001671 ATPase activator activity IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Mitochondrial iron-sulfur cluster biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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