ENSG00000100216


Homo sapiens

Features
Gene ID: ENSG00000100216
  
Biological name :TOMM22
  
Synonyms : Q9NS69 / TOMM22 / translocase of outer mitochondrial membrane 22
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 38681948
Gene end: 38685421
  
Corresponding Affymetrix probe sets: 217960_s_at (Human Genome U133 Plus 2.0 Array)   222474_s_at (Human Genome U133 Plus 2.0 Array)   229076_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216034
NCBI entrez gene - 56993     See in Manteia.
OMIM - 607046
RefSeq - NM_020243
RefSeq Peptide - NP_064628
swissprot - Q549C5
swissprot - Q9NS69
Ensembl - ENSG00000100216
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tomm22ENSDARG00000045146Danio rerio
 TOMM22ENSGALG00000019316Gallus gallus
 Q9CPQ3ENSMUSG00000022427Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005683  Mitochondrial import receptor subunit Tom22


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006626 protein targeting to mitochondrion TAS
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0030150 protein import into mitochondrial matrix IBA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045040 protein import into mitochondrial outer membrane IDA
 biological_processGO:0051204 protein insertion into mitochondrial membrane IEA
 biological_processGO:0071806 protein transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005742 mitochondrial outer membrane translocase complex IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008320 protein transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Pink/Parkin Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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