ENSG00000100605


Homo sapiens

Features
Gene ID: ENSG00000100605
  
Biological name :ITPK1
  
Synonyms : inositol-tetrakisphosphate 1-kinase / ITPK1 / Q13572
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.12
Gene start: 92936914
Gene end: 93116320
  
Corresponding Affymetrix probe sets: 210197_at (Human Genome U133 Plus 2.0 Array)   210740_s_at (Human Genome U133 Plus 2.0 Array)   217710_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452230
Ensembl peptide - ENSP00000451893
Ensembl peptide - ENSP00000452258
Ensembl peptide - ENSP00000267615
Ensembl peptide - ENSP00000346272
Ensembl peptide - ENSP00000450421
Ensembl peptide - ENSP00000451091
Ensembl peptide - ENSP00000451154
NCBI entrez gene - 3705     See in Manteia.
OMIM - 601838
RefSeq - XM_017021264
RefSeq - NM_001142593
RefSeq - NM_001142594
RefSeq - NM_014216
RefSeq - XM_017021262
RefSeq - XM_017021263
RefSeq Peptide - NP_001136065
RefSeq Peptide - NP_001136066
RefSeq Peptide - NP_055031
swissprot - G3V4M9
swissprot - G3V588
swissprot - G3V5A3
swissprot - G3V3C0
swissprot - A0A024R6H3
swissprot - Q13572
Ensembl - ENSG00000100605
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itpk1aENSDARG00000013056Danio rerio
 itpk1bENSDARG00000070583Danio rerio
 ITPK1ENSGALG00000034898Gallus gallus
 Itpk1ENSMUSG00000057963Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008656  Inositol-tetrakisphosphate 1-kinase
 IPR011761  ATP-grasp fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0032957 inositol trisphosphate metabolic process IEA
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003824 catalytic activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047325 inositol tetrakisphosphate 1-kinase activity IEA
 molecular_functionGO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity TAS
 molecular_functionGO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity IEA
 molecular_functionGO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity IEA
 molecular_functionGO:0052825 inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity TAS
 molecular_functionGO:0052830 inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity TAS
 molecular_functionGO:0052831 inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity TAS
 molecular_functionGO:0052835 inositol-3,4,6-trisphosphate 1-kinase activity TAS


Pathways (from Reactome)
Pathway description
Synthesis of pyrophosphates in the cytosol
Synthesis of IP3 and IP4 in the cytosol
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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