ENSG00000100664


Homo sapiens

Features
Gene ID: ENSG00000100664
  
Biological name :EIF5
  
Synonyms : EIF5 / eukaryotic translation initiation factor 5 / P55010
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.32
Gene start: 103333544
Gene end: 103345025
  
Corresponding Affymetrix probe sets: 208290_s_at (Human Genome U133 Plus 2.0 Array)   208705_s_at (Human Genome U133 Plus 2.0 Array)   208706_s_at (Human Genome U133 Plus 2.0 Array)   208707_at (Human Genome U133 Plus 2.0 Array)   208708_x_at (Human Genome U133 Plus 2.0 Array)   241843_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453633
Ensembl peptide - ENSP00000453856
Ensembl peptide - ENSP00000453743
Ensembl peptide - ENSP00000216554
Ensembl peptide - ENSP00000376477
Ensembl peptide - ENSP00000452615
Ensembl peptide - ENSP00000452636
Ensembl peptide - ENSP00000452883
Ensembl peptide - ENSP00000453396
Ensembl peptide - ENSP00000453468
NCBI entrez gene - 1983     See in Manteia.
OMIM - 601710
RefSeq - NM_001969
RefSeq - NM_183004
RefSeq Peptide - NP_001960
RefSeq Peptide - NP_892116
swissprot - H0YMJ8
swissprot - H0YN40
swissprot - A0A024R6Q1
swissprot - P55010
swissprot - H0YK11
swissprot - H0YK29
swissprot - H0YLZ1
swissprot - H0YM54
Ensembl - ENSG00000100664
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif5ENSDARG00000003681Danio rerio
 EIF5ENSGALG00000011464Gallus gallus
 Eif5ENSMUSG00000021282Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002735  Translation initiation factor IF2/IF5
 IPR003307  W2 domain
 IPR016024  Armadillo-type fold
 IPR016189  Translation initiation factor IF2/IF5, N-terminal
 IPR016190  Translation initiation factor IF2/IF5, zinc-binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001731 formation of translation preinitiation complex IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation NAS
 biological_processGO:0006446 regulation of translational initiation IDA
 biological_processGO:0090630 activation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003743 translation initiation factor activity NAS
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008135 translation factor activity, RNA binding TAS
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0071074 eukaryotic initiation factor eIF2 binding IEA


Pathways (from Reactome)
Pathway description
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr