ENSG00000103187


Homo sapiens

Features
Gene ID: ENSG00000103187
  
Biological name :COTL1
  
Synonyms : coactosin like F-actin binding protein 1 / COTL1 / Q14019
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q24.1
Gene start: 84565594
Gene end: 84618077
  
Corresponding Affymetrix probe sets: 1556346_at (Human Genome U133 Plus 2.0 Array)   221059_s_at (Human Genome U133 Plus 2.0 Array)   224583_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262428
Ensembl peptide - ENSP00000480117
Ensembl peptide - ENSP00000457033
NCBI entrez gene - 23406     See in Manteia.
OMIM - 606748
RefSeq - NM_021149
RefSeq Peptide - NP_066972
swissprot - A0A087WWC7
swissprot - H3BT58
swissprot - Q14019
Ensembl - ENSG00000103187
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cotl1ENSDARG00000026829Danio rerio
 COTL1ENSGALG00000017644Gallus gallus
 Cotl1ENSMUSG00000031827Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002108  Actin-depolymerising factor homology domain
 IPR029006  ADF-H/Gelsolin-like domain superfamily
 IPR030502  Coactosin-like protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050832 defense response to fungus IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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