ENSG00000103429


Homo sapiens

Features
Gene ID: ENSG00000103429
  
Biological name :BFAR
  
Synonyms : BFAR / bifunctional apoptosis regulator / Q9NZS9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.12
Gene start: 14632815
Gene end: 14669236
  
Corresponding Affymetrix probe sets: 218056_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457561
Ensembl peptide - ENSP00000481225
Ensembl peptide - ENSP00000261658
Ensembl peptide - ENSP00000454476
Ensembl peptide - ENSP00000454606
Ensembl peptide - ENSP00000455428
Ensembl peptide - ENSP00000456358
Ensembl peptide - ENSP00000456869
Ensembl peptide - ENSP00000457165
NCBI entrez gene - 51283     See in Manteia.
RefSeq - XM_011522520
RefSeq - NM_016561
RefSeq - XM_005255350
RefSeq Peptide - NP_057645
RefSeq Peptide - NP_001317429
swissprot - H3BSU2
swissprot - H3BTG6
swissprot - H3BUB3
swissprot - A0A087WXR3
swissprot - Q9NZS9
swissprot - H3BMP2
swissprot - H3BPQ8
swissprot - H3BMY8
swissprot - H3BRQ5
Ensembl - ENSG00000103429
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BFARENSGALG00000003111Gallus gallus
 BfarENSMUSG00000022684Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0051865 protein autoubiquitination IDA
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:1903895 negative regulation of IRE1-mediated unfolded protein response IMP
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane NAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030674 protein binding, bridging IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA
 molecular_functionGO:0089720 caspase binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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