ENSG00000103485


Homo sapiens

Features
Gene ID: ENSG00000103485
  
Biological name :QPRT
  
Synonyms : Q15274 / QPRT / quinolinate phosphoribosyltransferase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 29679008
Gene end: 29698699
  
Corresponding Affymetrix probe sets: 204044_at (Human Genome U133 Plus 2.0 Array)   242414_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378782
Ensembl peptide - ENSP00000455183
NCBI entrez gene - 105369247     See in Manteia.
NCBI entrez gene - 23475     See in Manteia.
OMIM - 606248
RefSeq - XM_017023101
RefSeq - NM_001318249
RefSeq - NM_001318250
RefSeq - NM_014298
RefSeq - XM_005255223
RefSeq - XM_016999607
RefSeq Peptide - NP_055113
RefSeq Peptide - NP_001305178
RefSeq Peptide - NP_001305179
swissprot - Q15274
swissprot - H3BP73
Ensembl - ENSG00000103485
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 QprtENSMUSG00000030674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC009086.2ENSG0000027766955


Protein motifs (from Interpro)
Interpro ID Name
 IPR002638  Quinolinate phosphoribosyl transferase, C-terminal
 IPR004393  Nicotinate-nucleotide pyrophosphorylase
 IPR013785  Aldolase-type TIM barrel
 IPR022412  Quinolinate phosphoribosyl transferase, N-terminal
 IPR027277  Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD
 IPR036068  Nicotinate phosphoribosyltransferase-like, C-terminal
 IPR037128  Quinolinate phosphoribosyl transferase, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009435 NAD biosynthetic process IEA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019674 NAD metabolic process TAS
 biological_processGO:0034213 quinolinate catabolic process IDA
 biological_processGO:0051259 protein complex oligomerization IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016763 transferase activity, transferring pentosyl groups IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Nicotinate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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