ENSG00000105298


Homo sapiens

Features
Gene ID: ENSG00000105298
  
Biological name :CACTIN
  
Synonyms : CACTIN / cactin, spliceosome C complex subunit / Q8WUQ7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 3610641
Gene end: 3626815
  
Corresponding Affymetrix probe sets: 213815_x_at (Human Genome U133 Plus 2.0 Array)   214892_x_at (Human Genome U133 Plus 2.0 Array)   215954_s_at (Human Genome U133 Plus 2.0 Array)   237990_x_at (Human Genome U133 Plus 2.0 Array)   240373_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467788
Ensembl peptide - ENSP00000221899
Ensembl peptide - ENSP00000248420
Ensembl peptide - ENSP00000415078
Ensembl peptide - ENSP00000464898
Ensembl peptide - ENSP00000465751
Ensembl peptide - ENSP00000466600
Ensembl peptide - ENSP00000467149
NCBI entrez gene - 58509     See in Manteia.
RefSeq - XM_011528160
RefSeq - NM_001080543
RefSeq - NM_021231
RefSeq Peptide - NP_001074012
RefSeq Peptide - NP_067054
swissprot - K7EIU6
swissprot - K7EQE3
swissprot - K7ENY9
swissprot - K7EMQ0
swissprot - Q8WUQ7
Ensembl - ENSG00000105298
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cactinENSDARG00000059866Danio rerio
 CACTINENSGALG00000024391Gallus gallus
 CactinENSMUSG00000034889Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018816  Cactin, central domain
 IPR019134  Cactin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IC
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032688 negative regulation of interferon-beta production IMP
 biological_processGO:0032717 negative regulation of interleukin-8 production IDA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IDA
 biological_processGO:0034122 negative regulation of toll-like receptor signaling pathway IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0060339 negative regulation of type I interferon-mediated signaling pathway IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:0071347 cellular response to interleukin-1 IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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