ENSG00000105559


Homo sapiens

Features
Gene ID: ENSG00000105559
  
Biological name :PLEKHA4
  
Synonyms : pleckstrin homology domain containing A4 / PLEKHA4 / Q9H4M7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.33
Gene start: 48837097
Gene end: 48868632
  
Corresponding Affymetrix probe sets: 219011_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472636
Ensembl peptide - ENSP00000471274
Ensembl peptide - ENSP00000471462
Ensembl peptide - ENSP00000263265
Ensembl peptide - ENSP00000347683
Ensembl peptide - ENSP00000469096
Ensembl peptide - ENSP00000469211
NCBI entrez gene - 57664     See in Manteia.
OMIM - 607769
RefSeq - XM_017027037
RefSeq - NM_001161354
RefSeq - NM_020904
RefSeq - XM_005259107
RefSeq - XM_006723301
RefSeq - XM_011527157
RefSeq - XM_011527158
RefSeq - XM_011527159
RefSeq - XM_011527160
RefSeq Peptide - NP_001154826
RefSeq Peptide - NP_065955
swissprot - M0R0V1
swissprot - M0R2K5
swissprot - M0QXJ3
swissprot - M0QXD9
swissprot - Q9H4M7
swissprot - M0R0J1
Ensembl - ENSG00000105559
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-234p6.5ENSDARG00000071460Danio rerio
 Plekha4ENSMUSG00000040428Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6IQ23 / PLEKHA7 / pleckstrin homology domain containing A7ENSG0000016668928
Q9HAU0 / PLEKHA5 / pleckstrin homology domain containing A5ENSG0000005212626
Q9Y2H5 / PLEKHA6 / pleckstrin homology domain containing A6ENSG0000014385024


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IDA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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