ENSG00000106305


Homo sapiens

Features
Gene ID: ENSG00000106305
  
Biological name :AIMP2
  
Synonyms : AIMP2 / aminoacyl tRNA synthetase complex interacting multifunctional protein 2 / Q13155
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p22.1
Gene start: 6009245
Gene end: 6023834
  
Corresponding Affymetrix probe sets: 202138_x_at (Human Genome U133 Plus 2.0 Array)   209971_x_at (Human Genome U133 Plus 2.0 Array)   209972_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000383327
Ensembl peptide - ENSP00000392519
Ensembl peptide - ENSP00000223029
Ensembl peptide - ENSP00000378658
NCBI entrez gene - 7965     See in Manteia.
OMIM - 600859
RefSeq - XM_011515519
RefSeq - NM_006303
RefSeq - XM_005249847
RefSeq - XM_005249848
RefSeq - XM_005249850
RefSeq - XM_006715772
RefSeq Peptide - NP_001313539
RefSeq Peptide - NP_001313540
RefSeq Peptide - NP_006294
RefSeq Peptide - NP_001313538
swissprot - A8MU58
swissprot - F8W950
swissprot - F8WCL2
swissprot - A0A024QZY1
swissprot - Q13155
Ensembl - ENSG00000106305
  
Related genetic diseases (OMIM): 618006 - Leukodystrophy, hypomyelinating, 17, 618006
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aimp2ENSDARG00000018903Danio rerio
 AIMP2ENSGALG00000003400Gallus gallus
 Aimp2ENSMUSG00000029610Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004046  Glutathione S-transferase, C-terminal
 IPR031889  AIMP2, lysyl-tRNA synthetase binding domain
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0060510 type II pneumocyte differentiation IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:1901216 positive regulation of neuron death IEA
 biological_processGO:1903632 positive regulation of aminoacyl-tRNA ligase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0017101 aminoacyl-tRNA synthetase multienzyme complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA


Pathways (from Reactome)
Pathway description
SeMet incorporation into proteins
Cytosolic tRNA aminoacylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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