ENSG00000108702


Homo sapiens

Features
Gene ID: ENSG00000108702
  
Biological name :CCL1
  
Synonyms : CCL1 / C-C motif chemokine ligand 1 / P22362
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 34360328
Gene end: 34363231
  
Corresponding Affymetrix probe sets: 207533_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000225842
NCBI entrez gene - 6346     See in Manteia.
OMIM - 182281
RefSeq - NM_002981
RefSeq Peptide - NP_002972
swissprot - P22362
Ensembl - ENSG00000108702
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCL1ENSGALG00000002329Gallus gallus
 Ccl1ENSMUSG00000020702Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006874 cellular calcium ion homeostasis TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:0090026 positive regulation of monocyte chemotaxis IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IDA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000179934 CCR8 / P51685 / C-C motif chemokine receptor 8  / complex / reaction






 

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