ENSG00000109255


Homo sapiens

Features
Gene ID: ENSG00000109255
  
Biological name :NMU
  
Synonyms : neuromedin U / NMU / P48645
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q12
Gene start: 55595229
Gene end: 55636698
  
Corresponding Affymetrix probe sets: 206023_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264218
Ensembl peptide - ENSP00000424246
Ensembl peptide - ENSP00000422870
Ensembl peptide - ENSP00000422399
NCBI entrez gene - 10874     See in Manteia.
OMIM - 605103
RefSeq - XM_011534368
RefSeq - NM_001292045
RefSeq - NM_001292046
RefSeq - NM_006681
RefSeq - XM_011534367
RefSeq Peptide - NP_001278975
RefSeq Peptide - NP_001278974
RefSeq Peptide - NP_006672
swissprot - A0A0B4J202
swissprot - D6RBC9
swissprot - A0A250SH36
swissprot - E9PDJ7
swissprot - P48645
Ensembl - ENSG00000109255
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nmuENSDARG00000043299Danio rerio
 NMUENSGALG00000020151Gallus gallus
 NmuENSMUSG00000029236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008200  Neuromedin U, C-terminal
 IPR018070  Neuromedin U, amidation site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001659 temperature homeostasis IEA
 biological_processGO:0001696 gastric acid secretion IEA
 biological_processGO:0006940 regulation of smooth muscle contraction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0009648 photoperiodism IEA
 biological_processGO:0010460 positive regulation of heart rate IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0031652 positive regulation of heat generation IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0044497 positive regulation of blood pressure in other organism IEA
 biological_processGO:0045187 regulation of circadian sleep/wake cycle, sleep IEA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IEA
 biological_processGO:0046887 positive regulation of hormone secretion IEA
 biological_processGO:0050806 positive regulation of synaptic transmission IEA
 biological_processGO:0060259 regulation of feeding behavior IEA
 biological_processGO:0060455 negative regulation of gastric acid secretion IEA
 biological_processGO:0097009 energy homeostasis IEA
 biological_processGO:0120061 negative regulation of gastric emptying IEA
 biological_processGO:0120069 positive regulation of stomach fundus smooth muscle contraction IEA
 biological_processGO:1902722 positive regulation of prolactin secretion IEA
 biological_processGO:1903999 negative regulation of eating behavior IEA
 biological_processGO:1904058 positive regulation of sensory perception of pain IEA
 biological_processGO:2000252 negative regulation of feeding behavior IEA
 biological_processGO:2000821 regulation of grooming behavior IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0043195 terminal bouton IEA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031839 type 1 neuromedin U receptor binding IDA
 molecular_functionGO:0031840 type 2 neuromedin U receptor binding IDA
 molecular_functionGO:0042922 neuromedin U receptor binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132911 NMUR2 / Q9GZQ4 / neuromedin U receptor 2  / reaction / complex
 ENSG00000171596 NMUR1 / Q9HB89 / neuromedin U receptor 1  / reaction / complex






 

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