ENSG00000110200


Homo sapiens

Features
Gene ID: ENSG00000110200
  
Biological name :ANAPC15
  
Synonyms : ANAPC15 / anaphase promoting complex subunit 15 / P60006
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.4
Gene start: 72106378
Gene end: 72112780
  
Corresponding Affymetrix probe sets: 204218_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446383
Ensembl peptide - ENSP00000445212
Ensembl peptide - ENSP00000446412
Ensembl peptide - ENSP00000227618
Ensembl peptide - ENSP00000389730
Ensembl peptide - ENSP00000437360
Ensembl peptide - ENSP00000437683
Ensembl peptide - ENSP00000439362
Ensembl peptide - ENSP00000439403
Ensembl peptide - ENSP00000440002
Ensembl peptide - ENSP00000440380
Ensembl peptide - ENSP00000440983
Ensembl peptide - ENSP00000441774
Ensembl peptide - ENSP00000443383
Ensembl peptide - ENSP00000443645
Ensembl peptide - ENSP00000443911
NCBI entrez gene - 25906     See in Manteia.
OMIM - 614717
RefSeq - XM_017017497
RefSeq - NM_001278485
RefSeq - NM_001278486
RefSeq - NM_001278487
RefSeq - NM_001278488
RefSeq - NM_001278489
RefSeq - NM_001278490
RefSeq - NM_001278491
RefSeq - NM_001278492
RefSeq - NM_001278493
RefSeq - NM_001278494
RefSeq - NM_014042
RefSeq - XM_017017488
RefSeq - XM_017017489
RefSeq - XM_017017490
RefSeq - XM_017017491
RefSeq - XM_017017492
RefSeq - XM_017017493
RefSeq - XM_017017494
RefSeq - XM_017017495
RefSeq - XM_017017496
RefSeq Peptide - NP_001265415
RefSeq Peptide - NP_001265419
RefSeq Peptide - NP_001265420
RefSeq Peptide - NP_001265421
RefSeq Peptide - NP_001265422
RefSeq Peptide - NP_001265423
RefSeq Peptide - NP_001317250
RefSeq Peptide - NP_054761
RefSeq Peptide - NP_001265414
RefSeq Peptide - NP_001265416
RefSeq Peptide - NP_001265417
RefSeq Peptide - NP_001265418
swissprot - F5GWM6
swissprot - F5GXB9
swissprot - F5H2T3
swissprot - F5H3R3
swissprot - F5H6E4
swissprot - F8WDQ6
swissprot - G5EA39
swissprot - A0A024R5G0
swissprot - P60006
Ensembl - ENSG00000110200
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1QY75ENSDARG00000101285Danio rerio
 ENSGALG00000032499Gallus gallus
 Anapc15-psENSMUSG00000074780Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR026182  Anaphase-promoting complex subunit 15


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051436 obsolete negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS
 biological_processGO:0051437 obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition TAS
 biological_processGO:0051439 obsolete regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS
 biological_processGO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 cellular_componentGO:0005829 cytosol TAS


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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