ENSG00000112874


Homo sapiens

Features
Gene ID: ENSG00000112874
  
Biological name :NUDT12
  
Synonyms : nudix hydrolase 12 / NUDT12 / Q9BQG2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q21.2
Gene start: 103548855
Gene end: 103562793
  
Corresponding Affymetrix probe sets: 1562775_at (Human Genome U133 Plus 2.0 Array)   223535_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424521
Ensembl peptide - ENSP00000230792
NCBI entrez gene - 83594     See in Manteia.
OMIM - 609232
RefSeq - XM_005272097
RefSeq - NM_001300741
RefSeq - NM_031438
RefSeq - XM_005272095
RefSeq Peptide - NP_113626
RefSeq Peptide - NP_001287670
swissprot - Q9BQG2
swissprot - E7EM93
Ensembl - ENSG00000112874
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt12ENSDARG00000100813Danio rerio
 NUDT12ENSGALG00000015268Gallus gallus
 Nudt12ENSMUSG00000024228Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NUDT13 / Q86X67 / nudix hydrolase 13ENSG0000016632125


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR002110  Ankyrin repeat
 IPR015375  NADH pyrophosphatase-like, N-terminal
 IPR015376  Zinc ribbon, NADH pyrophosphatase
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006742 NADP catabolic process IDA
 biological_processGO:0019677 NAD catabolic process IDA
 biological_processGO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005782 peroxisomal matrix TAS
 molecular_functionGO:0000210 NAD+ diphosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035529 NADH pyrophosphatase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr