ENSG00000112877


Homo sapiens

Features
Gene ID: ENSG00000112877
  
Biological name :CEP72
  
Synonyms : centrosomal protein 72 / CEP72 / Q9P209
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p15.33
Gene start: 612272
Gene end: 667168
  
Corresponding Affymetrix probe sets: 219531_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264935
NCBI entrez gene - 55722     See in Manteia.
OMIM - 616475
RefSeq - XM_017009627
RefSeq - NM_018140
RefSeq - XM_011514064
RefSeq - XM_017009626
RefSeq - XM_005248322
RefSeq - XM_011514063
RefSeq Peptide - NP_060610
swissprot - Q9P209
Ensembl - ENSG00000112877
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep72ENSDARG00000105258Danio rerio
 Cep72ENSMUSG00000021572Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRC36 / Q1X8D7 / leucine rich repeat containing 36ENSG0000015970826


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003603  U2A"/phosphoprotein 32 family A, C-terminal
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0007051 spindle organization IMP
 biological_processGO:0007099 centriole replication IMP
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0033566 gamma-tubulin complex localization IMP
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 biological_processGO:1904779 regulation of protein localization to centrosome IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0034451 centriolar satellite IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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