ENSG00000114902


Homo sapiens

Features
Gene ID: ENSG00000114902
  
Biological name :SPCS1
  
Synonyms : Q9Y6A9 / signal peptidase complex subunit 1 / SPCS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.1
Gene start: 52704955
Gene end: 52711146
  
Corresponding Affymetrix probe sets: 217927_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391610
Ensembl peptide - ENSP00000478310
Ensembl peptide - ENSP00000473265
Ensembl peptide - ENSP00000233025
NCBI entrez gene - 28972     See in Manteia.
OMIM - 610358
RefSeq - NM_014041
RefSeq Peptide - NP_054760
swissprot - C9JBL1
swissprot - Q9Y6A9
swissprot - X6R2S6
Ensembl - ENSG00000114902
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spcs1ENSDARG00000059298Danio rerio
 SPCS1ENSGALG00000001655Gallus gallus
 Spcs1ENSMUSG00000021917Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009542  Microsomal signal peptidase 12kDa subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006465 signal peptide processing IEA
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0045047 protein targeting to ER IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005787 signal peptidase complex IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043022 ribosome binding IEA


Pathways (from Reactome)
Pathway description
SRP-dependent cotranslational protein targeting to membrane
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
Synthesis, secretion, and deacylation of Ghrelin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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