ENSG00000114999


Homo sapiens

Features
Gene ID: ENSG00000114999
  
Biological name :TTL
  
Synonyms : Q8NG68 / TTL / tubulin tyrosine ligase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q14.1
Gene start: 112482154
Gene end: 112541739
  
Corresponding Affymetrix probe sets: 1555374_at (Human Genome U133 Plus 2.0 Array)   1559680_at (Human Genome U133 Plus 2.0 Array)   224896_s_at (Human Genome U133 Plus 2.0 Array)   224908_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000233336
NCBI entrez gene - 150465     See in Manteia.
OMIM - 608291
RefSeq - XM_011510665
RefSeq - NM_153712
RefSeq - XM_005263599
RefSeq Peptide - NP_714923
swissprot - Q8NG68
Ensembl - ENSG00000114999
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttlENSDARG00000062418Danio rerio
 TTLENSGALG00000008614Gallus gallus
 TtlENSMUSG00000027394Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004344  Tubulin-tyrosine ligase/Tubulin polyglutamylase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0018166 C-terminal protein-tyrosinylation IMP
 biological_processGO:0030516 regulation of axon extension IEA
 biological_processGO:0045931 positive regulation of mitotic cell cycle IMP
 biological_processGO:0090235 regulation of metaphase plate congression IMP
 cellular_componentGO:0005623 cell IMP
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004835 tubulin-tyrosine ligase activity IMP
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Carboxyterminal post-translational modifications of tubulin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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