ENSG00000115523


Homo sapiens

Features
Gene ID: ENSG00000115523
  
Biological name :GNLY
  
Synonyms : GNLY / granulysin / P22749
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p11.2
Gene start: 85685175
Gene end: 85698854
  
Corresponding Affymetrix probe sets: 205495_s_at (Human Genome U133 Plus 2.0 Array)   37145_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436423
Ensembl peptide - ENSP00000263863
Ensembl peptide - ENSP00000387116
Ensembl peptide - ENSP00000434467
NCBI entrez gene - 10578     See in Manteia.
OMIM - 188855
RefSeq - XM_005264087
RefSeq - NM_001302758
RefSeq - NM_006433
RefSeq - NM_012483
RefSeq - XM_005264084
RefSeq - XM_005264085
RefSeq Peptide - NP_006424
RefSeq Peptide - NP_036615
RefSeq Peptide - NP_001289687
swissprot - H0YDW8
swissprot - P22749
swissprot - B4E3H9
Ensembl - ENSG00000115523
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008138  Saposin B type, region 2
 IPR008139  Saposin B type domain
 IPR011001  Saposin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002818 intracellular defense response IDA
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0031640 killing of cells of other organism IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0050832 defense response to fungus IEA
 biological_processGO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0044194 cytolytic granule IDA
 cellular_componentGO:0097013 phagocytic vesicle lumen TAS


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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contact: otassy@igbmc.fr