ENSG00000115828


Homo sapiens

Features
Gene ID: ENSG00000115828
  
Biological name :QPCT
  
Synonyms : glutaminyl-peptide cyclotransferase / Q16769 / QPCT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p22.2
Gene start: 37344574
Gene end: 37373322
  
Corresponding Affymetrix probe sets: 205174_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000344829
Ensembl peptide - ENSP00000389227
Ensembl peptide - ENSP00000385391
NCBI entrez gene - 25797     See in Manteia.
OMIM - 607065
RefSeq - NM_012413
RefSeq Peptide - NP_036545
swissprot - C9JS14
swissprot - B5MCZ9
swissprot - Q16769
Ensembl - ENSG00000115828
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 qpctENSDARG00000089717Danio rerio
 QPCTENSGALG00000032440Gallus gallus
 QpctENSMUSG00000024084Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
QPCTL / Q9NXS2 / glutaminyl-peptide cyclotransferase likeENSG0000001147847


Protein motifs (from Interpro)
Interpro ID Name
 IPR007484  Peptidase M28
 IPR037457  M28 Zn-Peptidase Glutaminyl Cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904724 tertiary granule lumen TAS
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016603 glutaminyl-peptide cyclotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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