ENSG00000116260


Homo sapiens

Features
Gene ID: ENSG00000116260
  
Biological name :QSOX1
  
Synonyms : O00391 / QSOX1 / quiescin sulfhydryl oxidase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q25.2
Gene start: 180154834
Gene end: 180204030
  
Corresponding Affymetrix probe sets: 201482_at (Human Genome U133 Plus 2.0 Array)   226706_at (Human Genome U133 Plus 2.0 Array)   230523_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356572
Ensembl peptide - ENSP00000402170
Ensembl peptide - ENSP00000375883
Ensembl peptide - ENSP00000356574
NCBI entrez gene - 5768     See in Manteia.
OMIM - 603120
RefSeq - NM_002826
RefSeq - NM_001004128
RefSeq Peptide - NP_001004128
RefSeq Peptide - NP_002817
swissprot - O00391
swissprot - A0A140VKE5
swissprot - H0Y5Z8
swissprot - A8MXT8
Ensembl - ENSG00000116260
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 qsox1ENSDARG00000039459Danio rerio
 QSOX1ENSGALG00000003933Gallus gallus
 Qsox1ENSMUSG00000033684Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
QSOX2 / Q6ZRP7 / quiescin sulfhydryl oxidase 2ENSG0000016566134


Protein motifs (from Interpro)
Interpro ID Name
 IPR013766  Thioredoxin domain
 IPR017905  ERV/ALR sulfhydryl oxidase domain
 IPR036249  Thioredoxin-like superfamily
 IPR036774  ERV/ALR sulfhydryl oxidase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0016242 negative regulation of macroautophagy IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane IDA
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045171 intercellular bridge IDA
 cellular_componentGO:0070062 extracellular exosome IDA
 cellular_componentGO:1904724 tertiary granule lumen TAS
 molecular_functionGO:0003756 protein disulfide isomerase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016971 flavin-linked sulfhydryl oxidase activity IDA
 molecular_functionGO:0016972 thiol oxidase activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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