ENSG00000117505


Homo sapiens

Features
Gene ID: ENSG00000117505
  
Biological name :DR1
  
Synonyms : down-regulator of transcription 1 / DR1 / Q01658
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.1
Gene start: 93345888
Gene end: 93369498
  
Corresponding Affymetrix probe sets: 1558236_at (Human Genome U133 Plus 2.0 Array)   1558237_x_at (Human Genome U133 Plus 2.0 Array)   207654_x_at (Human Genome U133 Plus 2.0 Array)   209187_at (Human Genome U133 Plus 2.0 Array)   209188_x_at (Human Genome U133 Plus 2.0 Array)   216652_s_at (Human Genome U133 Plus 2.0 Array)   216653_at (Human Genome U133 Plus 2.0 Array)   235585_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359290
Ensembl peptide - ENSP00000359295
NCBI entrez gene - 1810     See in Manteia.
OMIM - 601482
RefSeq - NM_001938
RefSeq Peptide - NP_001929
swissprot - Q01658
swissprot - Q658N3
Ensembl - ENSG00000117505
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dr1ENSDARG00000105098Danio rerio
 DR1ENSGALG00000005858Gallus gallus
 Dr1ENSMUSG00000029265Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003958  Transcription factor CBF/NF-Y/archaeal histone domain
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0043966 histone H3 acetylation IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005671 Ada2/Gcn5/Ada3 transcription activator complex IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding TAS
 molecular_functionGO:0017025 TBP-class protein binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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