ENSG00000118363


Homo sapiens

Features
Gene ID: ENSG00000118363
  
Biological name :SPCS2
  
Synonyms : Q15005 / signal peptidase complex subunit 2 / SPCS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 74949247
Gene end: 74979031
  
Corresponding Affymetrix probe sets: 201239_s_at (Human Genome U133 Plus 2.0 Array)   201240_s_at (Human Genome U133 Plus 2.0 Array)   243570_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433439
Ensembl peptide - ENSP00000478550
Ensembl peptide - ENSP00000436759
Ensembl peptide - ENSP00000434706
Ensembl peptide - ENSP00000434248
Ensembl peptide - ENSP00000263672
NCBI entrez gene - 9789     See in Manteia.
RefSeq - NM_014752
RefSeq Peptide - NP_055567
swissprot - E9PI68
swissprot - A0A087WUC6
swissprot - H0YE04
swissprot - E9PRB9
swissprot - Q15005
swissprot - E9PL01
Ensembl - ENSG00000118363
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spcs2ENSDARG00000042823Danio rerio
 SPCS2ENSGALG00000019036Gallus gallus
 Spcs2ENSMUSG00000035227Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009582  Signal peptidase complex subunit 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006465 signal peptide processing IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0045047 protein targeting to ER IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005787 signal peptidase complex IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
SRP-dependent cotranslational protein targeting to membrane
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
Synthesis, secretion, and deacylation of Ghrelin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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