ENSG00000120334


Homo sapiens

Features
Gene ID: ENSG00000120334
  
Biological name :CENPL
  
Synonyms : CENPL / centromere protein L / Q8N0S6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.1
Gene start: 173799550
Gene end: 173824720
  
Corresponding Affymetrix probe sets: 1554271_a_at (Human Genome U133 Plus 2.0 Array)   232065_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356683
Ensembl peptide - ENSP00000323543
Ensembl peptide - ENSP00000348527
NCBI entrez gene - 91687     See in Manteia.
OMIM - 611503
RefSeq - NM_001127181
RefSeq - NM_001171182
RefSeq - NM_033319
RefSeq Peptide - NP_001120653
RefSeq Peptide - NP_001164653
RefSeq Peptide - NP_201576
swissprot - Q8N0S6
swissprot - A0A024R932
Ensembl - ENSG00000120334
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cenplENSDARG00000038802Danio rerio
 CENPLENSGALG00000038411Gallus gallus
 CenplENSMUSG00000026708Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR025204  Centromere subunit L


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0034080 CENP-A containing nucleosome assembly TAS
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr