ENSG00000120937


Homo sapiens

Features
Gene ID: ENSG00000120937
  
Biological name :NPPB
  
Synonyms : natriuretic peptide B / NPPB / P16860
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.22
Gene start: 11857464
Gene end: 11858931
  
Corresponding Affymetrix probe sets: 206801_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365651
NCBI entrez gene - 4879     See in Manteia.
OMIM - 600295
RefSeq - NM_002521
RefSeq Peptide - NP_002512
swissprot - P16860
Ensembl - ENSG00000120937
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NPPAENSGALG00000004574Gallus gallus
 NppbENSMUSG00000029019Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000663  Natriuretic peptide
 IPR002408  Natriuretic peptide, brain type
 IPR030480  Natriuretic peptide, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IDA
 biological_processGO:0006457 protein folding IDA
 biological_processGO:0007166 cell surface receptor signaling pathway NAS
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway IDA
 biological_processGO:0007589 body fluid secretion TAS
 biological_processGO:0008217 regulation of blood pressure NAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016525 negative regulation of angiogenesis TAS
 biological_processGO:0030308 negative regulation of cell growth NAS
 biological_processGO:0035810 positive regulation of urine volume TAS
 biological_processGO:0035815 positive regulation of renal sodium excretion TAS
 biological_processGO:0043114 regulation of vascular permeability TAS
 biological_processGO:0050880 regulation of blood vessel size IEA
 biological_processGO:0097746 regulation of blood vessel diameter NAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space NAS
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005179 hormone activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008613 diuretic hormone activity TAS
 molecular_functionGO:0051427 hormone receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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