ENSG00000121314


Homo sapiens

Features
Gene ID: ENSG00000121314
  
Biological name :TAS2R8
  
Synonyms : Q9NYW2 / TAS2R8 / taste 2 receptor member 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.2
Gene start: 10806051
Gene end: 10807293
  
Corresponding Affymetrix probe sets: 221398_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000240615
NCBI entrez gene - 50836     See in Manteia.
OMIM - 604794
RefSeq - NM_023918
RefSeq Peptide - NP_076407
swissprot - Q9NYW2
Ensembl - ENSG00000121314
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NYW3 / TAS2R7 / taste 2 receptor member 7ENSG0000012137747
Q9NYW1 / TAS2R9 / taste 2 receptor member 9ENSG0000012138146
Q9NYW6 / TAS2R3 / taste 2 receptor member 3ENSG0000012736240
Q9NYW0 / TAS2R10 / taste 2 receptor member 10ENSG0000012131837
P59542 / TAS2R19 / taste 2 receptor member 19ENSG0000021212435
P59540 / TAS2R46 / taste 2 receptor member 46ENSG0000022676135
Q7RTR8 / TAS2R42 / taste 2 receptor member 42ENSG0000018613634
P59544 / TAS2R50 / taste 2 receptor member 50ENSG0000021212634
P59543 / TAS2R20 / taste 2 receptor member 20ENSG0000025583733
P59541 / TAS2R30 / taste 2 receptor member 30ENSG0000025618833
P59537 / TAS2R43 / taste 2 receptor member 43ENSG0000025537432
Q9NYV8 / TAS2R14 / taste 2 receptor member 14ENSG0000021212732
Q9NYV9 / TAS2R13 / taste 2 receptor member 13ENSG0000021212831
P59538 / TAS2R31 / taste 2 receptor member 31ENSG0000025643631
P59535 / TAS2R40 / taste 2 receptor member 40ENSG0000022193730
P59534 / TAS2R39 / taste 2 receptor member 39ENSG0000023639828
P59536 / TAS2R41 / taste 2 receptor member 41ENSG0000022185528
Q9NYW7 / TAS2R1 / taste 2 receptor member 1ENSG0000016977727
Q9NYW5 / TAS2R4 / taste 2 receptor member 4ENSG0000012736426
Q9NYW4 / TAS2R5 / taste 2 receptor member 5ENSG0000012736626


Protein motifs (from Interpro)
Interpro ID Name
 IPR007960  Taste receptor type 2
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050909 sensory perception of taste IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008527 taste receptor activity TAS
 molecular_functionGO:0033038 bitter taste receptor activity IDA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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