ENSG00000122223


Homo sapiens

Features
Gene ID: ENSG00000122223
  
Biological name :CD244
  
Synonyms : CD244 / CD244 molecule / Q9BZW8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 160830160
Gene end: 160862855
  
Corresponding Affymetrix probe sets: 220307_at (Human Genome U133 Plus 2.0 Array)   234320_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000313619
Ensembl peptide - ENSP00000357012
Ensembl peptide - ENSP00000357013
Ensembl peptide - ENSP00000432636
NCBI entrez gene - 51744     See in Manteia.
OMIM - 605554
RefSeq - XM_011509623
RefSeq - NM_001166663
RefSeq - NM_001166664
RefSeq - NM_016382
RefSeq - XM_011509621
RefSeq - XM_011509622
RefSeq Peptide - NP_001160135
RefSeq Peptide - NP_001160136
RefSeq Peptide - NP_057466
swissprot - Q9BZW8
Ensembl - ENSG00000122223
  
Related genetic diseases (OMIM): 180300 - {Rheumatoid arthritis, susceptibility to}, 180300
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000040002Gallus gallus
 Cd244ENSMUSG00000004709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR024303  Natural killer cell receptor 2B4, immunoglobulin domain
 IPR024304  Natural killer cell receptor 2B4
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002323 natural killer cell activation involved in immune response IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0060732 positive regulation of inositol phosphate biosynthetic process IDA
 biological_processGO:0071663 positive regulation of granzyme B production IDA
 biological_processGO:1902715 positive regulation of interferon-gamma secretion IDA
 biological_processGO:2000484 positive regulation of interleukin-8 secretion IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042288 MHC class I protein binding IDA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000117091 CD48 / P09326 / CD48 molecule  / complex / reaction






 

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