ENSG00000122952


Homo sapiens

Features
Gene ID: ENSG00000122952
  
Biological name :ZWINT
  
Synonyms : O95229 / ZW10 interacting kinetochore protein / ZWINT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q21.1
Gene start: 56357228
Gene end: 56361275
  
Corresponding Affymetrix probe sets: 204026_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000322850
Ensembl peptide - ENSP00000363055
Ensembl peptide - ENSP00000378801
Ensembl peptide - ENSP00000473330
Ensembl peptide - ENSP00000354921
NCBI entrez gene - 11130     See in Manteia.
OMIM - 609177
RefSeq - XM_017015605
RefSeq - NM_001005413
RefSeq - NM_007057
RefSeq - NM_032997
RefSeq Peptide - NP_001005413
RefSeq Peptide - NP_008988
RefSeq Peptide - NP_127490
swissprot - O95229
swissprot - R4GMS7
swissprot - A6NH27
Ensembl - ENSG00000122952
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ZwintENSMUSG00000019923Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029092  ZW10 interactor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007093 mitotic cell cycle checkpoint IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051649 establishment of localization in cell IDA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IDA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0047485 protein N-terminus binding IPI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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contact: otassy@igbmc.fr