ENSG00000124102


Homo sapiens

Features
Gene ID: ENSG00000124102
  
Biological name :PI3
  
Synonyms : P19957 / peptidase inhibitor 3 / PI3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.12
Gene start: 45174876
Gene end: 45176544
  
Corresponding Affymetrix probe sets: 203691_at (Human Genome U133 Plus 2.0 Array)   41469_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000243924
NCBI entrez gene - 5266     See in Manteia.
OMIM - 182257
RefSeq - NM_002638
RefSeq Peptide - NP_002629
swissprot - P19957
Ensembl - ENSG00000124102
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002098  Seminal vesicle protein I
 IPR008197  WAP-type "four-disulfide core" domain
 IPR019541  Trappin protein transglutaminase-binding repeat
 IPR036645  Elafin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007620 copulation IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0018149 peptide cross-linking IDA
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0001533 cornified envelope IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004866 endopeptidase inhibitor activity TAS
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0030280 structural constituent of epidermis IDA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Antimicrobial peptides
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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