ENSG00000124731


Homo sapiens

Features
Gene ID: ENSG00000124731
  
Biological name :TREM1
  
Synonyms : Q9NP99 / TREM1 / triggering receptor expressed on myeloid cells 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.1
Gene start: 41267926
Gene end: 41286719
  
Corresponding Affymetrix probe sets: 219434_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000244709
Ensembl peptide - ENSP00000334284
Ensembl peptide - ENSP00000465345
Ensembl peptide - ENSP00000465688
NCBI entrez gene - 54210     See in Manteia.
OMIM - 605085
RefSeq - XM_017010957
RefSeq - NM_001242589
RefSeq - NM_001242590
RefSeq - NM_018643
RefSeq - XM_011514696
RefSeq - XM_017010956
RefSeq Peptide - NP_061113
RefSeq Peptide - NP_001229518
RefSeq Peptide - NP_001229519
swissprot - Q38L15
swissprot - Q9NP99
swissprot - K7EKM5
Ensembl - ENSG00000124731
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Trem1ENSMUSG00000042265Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006959 humoral immune response TAS
 biological_processGO:0035556 intracellular signal transduction TAS
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0097110 scaffold protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
DAP12 interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000011600 O43914 / TYROBP / TYRO protein tyrosine kinase binding protein  / reaction / complex






 

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