ENSG00000124920


Homo sapiens

Features
Gene ID: ENSG00000124920
  
Biological name :MYRF
  
Synonyms : myelin regulatory factor / MYRF / Q9Y2G1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q12.2
Gene start: 61752642
Gene end: 61788518
  
Corresponding Affymetrix probe sets: 204073_s_at (Human Genome U133 Plus 2.0 Array)   217462_at (Human Genome U133 Plus 2.0 Array)   217463_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000374253
Ensembl peptide - ENSP00000265460
Ensembl peptide - ENSP00000278836
NCBI entrez gene - 745     See in Manteia.
OMIM - 608329
RefSeq - XM_011545234
RefSeq - NM_001127392
RefSeq - NM_013279
RefSeq - XM_005274225
RefSeq - XM_005274226
RefSeq - XM_005274227
RefSeq - XM_005274228
RefSeq - XM_005274222
RefSeq - XM_005274223
RefSeq - XM_005274224
RefSeq Peptide - NP_001120864
RefSeq Peptide - NP_037411
swissprot - Q9Y2G1
swissprot - B4DHB2
Ensembl - ENSG00000124920
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myrfENSDARG00000078676Danio rerio
 MYRFENSGALG00000041253Gallus gallus
 MyrfENSMUSG00000036098Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYRFL / Q96LU7 / myelin regulatory factor-likeENSG0000016626832


Protein motifs (from Interpro)
Interpro ID Name
 IPR008967  p53-like transcription factor, DNA-binding
 IPR024061  NDT80 DNA-binding domain
 IPR025719  Myelin gene regulatory factor C-terminal domain 2
 IPR026932  Myelin gene regulatory factor C-terminal domain 1
 IPR026933  Myelin gene regulatory factor
 IPR030392  Intramolecular chaperone auto-processing domain
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR037141  NDT80 DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0014003 oligodendrocyte development ISS
 biological_processGO:0022010 central nervous system myelination ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031643 positive regulation of myelination ISS
 biological_processGO:0032286 central nervous system myelin maintenance ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0048709 oligodendrocyte differentiation ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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