ENSG00000125148


Homo sapiens

Features
Gene ID: ENSG00000125148
  
Biological name :MT2A
  
Synonyms : metallothionein 2A / MT2A / P02795
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q13
Gene start: 56608199
Gene end: 56609497
  
Corresponding Affymetrix probe sets: 212185_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000245185
Ensembl peptide - ENSP00000456804
NCBI entrez gene - 4502     See in Manteia.
OMIM - 156360
RefSeq - NM_005953
RefSeq Peptide - NP_005944
swissprot - P02795
swissprot - H3BSP9
Ensembl - ENSG00000125148
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MT1G / P13640 / metallothionein 1GENSG0000012514495
MT1E / P04732 / metallothionein 1EENSG0000016971593
MT1F / P04733 / metallothionein 1FENSG0000019841790
MT1X / P80297 / metallothionein 1XENSG0000018719390
MT1A / P04731 / metallothionein 1AENSG0000020536290
MT1H / P80294 / metallothionein 1HENSG0000020535889
MT1HL1 / P0DM35 / metallothionein 1H like 1ENSG0000024402087


Protein motifs (from Interpro)
Interpro ID Name
 IPR000006  Metallothionein, vertebrate
 IPR003019  Metallothionein
 IPR017854  Metallothionein domain superfamily
 IPR018064  Metallothionein, vertebrate, metal binding site
 IPR023587  Metallothionein domain superfamily, vertebrate


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006878 cellular copper ion homeostasis TAS
 biological_processGO:0010038 response to metal ion TAS
 biological_processGO:0035690 cellular response to drug IDA
 biological_processGO:0036016 cellular response to interleukin-3 IEP
 biological_processGO:0036018 cellular response to erythropoietin IEP
 biological_processGO:0045926 negative regulation of growth ISS
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0071294 cellular response to zinc ion IEP
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Metallothioneins bind metals
Interferon gamma signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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