ENSG00000125245


Homo sapiens

Features
Gene ID: ENSG00000125245
  
Biological name :GPR18
  
Synonyms : GPR18 / G protein-coupled receptor 18 / Q14330
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q32.3
Gene start: 99254714
Gene end: 99261744
  
Corresponding Affymetrix probe sets: 210279_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000343428
Ensembl peptide - ENSP00000380610
Ensembl peptide - ENSP00000380613
Ensembl peptide - ENSP00000401611
NCBI entrez gene - 2841     See in Manteia.
OMIM - 602042
RefSeq - XM_006719946
RefSeq - NM_001098200
RefSeq - NM_005292
RefSeq Peptide - NP_001091670
RefSeq Peptide - NP_005283
swissprot - Q14330
swissprot - Q5JUH9
swissprot - H9NIM1
Ensembl - ENSG00000125245
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr18ENSDARG00000062009Danio rerio
 GPR18ENSGALG00000022750Gallus gallus
 Gpr18ENSMUSG00000050350Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR20 / Q99678 / G protein-coupled receptor 20ENSG0000020488222
GPR55 / Q9Y2T6 / G protein-coupled receptor 55ENSG0000013589822
GPR35 / Q9HC97 / G protein-coupled receptor 35ENSG0000017862320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR028335  G protein-coupled receptor 18 orphan


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation IEA
 biological_processGO:0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation IEA
 biological_processGO:0002689 negative regulation of leukocyte chemotaxis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0030217 T cell differentiation IBA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IBA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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