ENSG00000125337


Homo sapiens

Features
Gene ID: ENSG00000125337
  
Biological name :KIF25
  
Synonyms : KIF25 / kinesin family member 25 / Q9UIL4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q27
Gene start: 167996241
Gene end: 168045089
  
Corresponding Affymetrix probe sets: 207682_s_at (Human Genome U133 Plus 2.0 Array)   208128_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000346401
Ensembl peptide - ENSP00000427464
Ensembl peptide - ENSP00000496229
Ensembl peptide - ENSP00000252688
Ensembl peptide - ENSP00000388878
NCBI entrez gene - 3834     See in Manteia.
OMIM - 603815
RefSeq - XM_011535803
RefSeq - NM_005355
RefSeq - NM_030615
RefSeq - XM_011535802
RefSeq Peptide - NP_085118
RefSeq Peptide - NP_005346
swissprot - Q9UIL4
swissprot - H0YAK6
Ensembl - ENSG00000125337
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif25ENSDARG00000017532Danio rerio
 KIF25ENSGALG00000011299Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KIFC3 / Q9BVG8 / kinesin family member C3ENSG0000014085933
KIFC1 / Q9BW19 / kinesin family member C1ENSG0000023764930
KIFC2 / Q96AC6 / kinesin family member C2ENSG0000016770228


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation TAS
 biological_processGO:0006996 organelle organization TAS
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0010507 negative regulation of autophagy IMP
 biological_processGO:0046603 negative regulation of mitotic centrosome separation IDA
 biological_processGO:0051289 protein homotetramerization ISS
 biological_processGO:0051294 establishment of spindle orientation IDA
 biological_processGO:0051647 nucleus localization IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex TAS
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003777 microtubule motor activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed ISS
 molecular_functionGO:0016887 ATPase activity IBA


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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