ENSG00000126460


Homo sapiens

Features
Gene ID: ENSG00000126460
  
Biological name :PRRG2
  
Synonyms : O14669 / proline rich and Gla domain 2 / PRRG2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.33
Gene start: 49580646
Gene end: 49591015
  
Corresponding Affymetrix probe sets: 205617_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000246794
Ensembl peptide - ENSP00000469258
Ensembl peptide - ENSP00000470401
NCBI entrez gene - 5639     See in Manteia.
OMIM - 604429
RefSeq - XM_011527124
RefSeq - NM_000951
RefSeq - NM_001316335
RefSeq - XM_006723286
RefSeq Peptide - NP_000942
RefSeq Peptide - NP_001303264
swissprot - M0QZA1
swissprot - O14669
swissprot - M0QXL9
Ensembl - ENSG00000126460
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prrg2ENSDARG00000087193Danio rerio
 Prrg2ENSMUSG00000007837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRRG4 / Q9BZD6 / proline rich and Gla domain 4ENSG0000013537835
PRRG1 / O14668 / proline rich and Gla domain 1ENSG0000013096225
PRRG3 / Q9BZD7 / proline rich and Gla domain 3ENSG0000013003224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain
 IPR017857  Coagulation factor-like, Gla domain superfamily
 IPR035972  Gamma-carboxyglutamic acid-rich (GLA) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr