ENSG00000128654


Homo sapiens

Features
Gene ID: ENSG00000128654
  
Biological name :MTX2
  
Synonyms : metaxin 2 / MTX2 / O75431
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q31.1
Gene start: 176269395
Gene end: 176338025
  
Corresponding Affymetrix probe sets: 203517_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414176
Ensembl peptide - ENSP00000398757
Ensembl peptide - ENSP00000402204
Ensembl peptide - ENSP00000403545
Ensembl peptide - ENSP00000249442
NCBI entrez gene - 10651     See in Manteia.
OMIM - 608555
RefSeq - XM_011510497
RefSeq - NM_001006635
RefSeq - NM_001319097
RefSeq - NM_001319098
RefSeq - NM_006554
RefSeq Peptide - NP_001306027
RefSeq Peptide - NP_001006636
RefSeq Peptide - NP_001306026
RefSeq Peptide - NP_006545
swissprot - F8WE26
swissprot - C9JNK6
swissprot - O75431
swissprot - C9JAZ1
swissprot - F8WCW1
Ensembl - ENSG00000128654
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtx2ENSDARG00000029415Danio rerio
 MTX2ENSGALG00000009264Gallus gallus
 Mtx2ENSMUSG00000027099Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTX1 / Q13505 / metaxin 1ENSG0000017317127
MTX3 / Q5HYI7 / metaxin 3ENSG0000017703421


Protein motifs (from Interpro)
Interpro ID Name
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR012336  Thioredoxin-like fold
 IPR019564  Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain
 IPR033468  Metaxin, glutathione S-transferase domain
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006626 protein targeting to mitochondrion IEA
 biological_processGO:0006839 mitochondrial transport TAS
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Cristae formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000173171 MTX1 / Q13505 / metaxin 1  / complex
 ENSG00000100347 Q9Y512 / SAMM50 / SAMM50 sorting and assembly machinery component  / complex






 

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