ENSG00000128908


Homo sapiens

Features
Gene ID: ENSG00000128908
  
Biological name :INO80
  
Synonyms : INO80 / INO80 complex subunit / Q9ULG1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q15.1
Gene start: 40978880
Gene end: 41116354
  
Corresponding Affymetrix probe sets: 225357_s_at (Human Genome U133 Plus 2.0 Array)   229356_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452806
Ensembl peptide - ENSP00000483661
Ensembl peptide - ENSP00000454057
Ensembl peptide - ENSP00000453677
Ensembl peptide - ENSP00000355205
Ensembl peptide - ENSP00000384686
NCBI entrez gene - 54617     See in Manteia.
OMIM - 610169
RefSeq - NM_017553
RefSeq - XM_011521685
RefSeq - XM_011521686
RefSeq Peptide - NP_060023
swissprot - Q9ULG1
swissprot - H0YNL3
swissprot - A0A024R9R7
swissprot - H0YKH3
swissprot - H0YMN5
swissprot - A0A087X0U7
Ensembl - ENSG00000128908
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ino80ENSDARG00000070432Danio rerio
 INO80ENSGALG00000008553Gallus gallus
 Ino80ENSMUSG00000034154Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR011989  Armadillo-like helical
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR020838  DBINO domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031047  DNA helicase Ino80


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IMP
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010571 positive regulation of nuclear cell cycle DNA replication IMP
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030307 positive regulation of cell growth IMP
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0034644 cellular response to UV IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0051225 spindle assembly IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070914 UV-damage excision repair IMP
 biological_processGO:0071479 cellular response to ionizing radiation IMP
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0031011 Ino80 complex IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003678 DNA helicase activity IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0043014 alpha-tubulin binding IMP


Pathways (from Reactome)
Pathway description
UCH proteinases
DNA Damage Recognition in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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