ENSG00000129128


Homo sapiens

Features
Gene ID: ENSG00000129128
  
Biological name :SPCS3
  
Synonyms : P61009 / signal peptidase complex subunit 3 / SPCS3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q34.2
Gene start: 176319964
Gene end: 176332245
  
Corresponding Affymetrix probe sets: 218817_at (Human Genome U133 Plus 2.0 Array)   221844_x_at (Human Genome U133 Plus 2.0 Array)   222753_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427463
NCBI entrez gene - 60559     See in Manteia.
RefSeq - NM_021928
RefSeq Peptide - NP_068747
swissprot - P61009
Ensembl - ENSG00000129128
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spcs3ENSDARG00000089976Danio rerio
 SPCS3ENSGALG00000010839Gallus gallus
 Arxes1ENSMUSG00000048355Mus musculus
 Arxes2ENSMUSG00000048040Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007653  Signal peptidase complex subunit 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006465 signal peptide processing IBA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0045047 protein targeting to ER IBA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005787 signal peptidase complex IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0008233 peptidase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
SRP-dependent cotranslational protein targeting to membrane
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
Synthesis, secretion, and deacylation of Ghrelin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr