ENSG00000130038


Homo sapiens

Features
Gene ID: ENSG00000130038
  
Biological name :CRACR2A
  
Synonyms : calcium release activated channel regulator 2A / CRACR2A / Q9BSW2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.32
Gene start: 3606633
Gene end: 3764819
  
Corresponding Affymetrix probe sets: 1560874_at (Human Genome U133 Plus 2.0 Array)   223955_at (Human Genome U133 Plus 2.0 Array)   228752_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000252322
Ensembl peptide - ENSP00000331047
Ensembl peptide - ENSP00000409382
Ensembl peptide - ENSP00000438777
NCBI entrez gene - 84766     See in Manteia.
OMIM - 614178
RefSeq - XM_011521038
RefSeq - NM_032680
RefSeq - XM_006719021
RefSeq - XM_011521034
RefSeq - XM_011521036
RefSeq - XM_011521037
RefSeq - NM_001144958
RefSeq Peptide - NP_001138430
RefSeq Peptide - NP_116069
swissprot - H7BXT2
swissprot - Q9BSW2
swissprot - H0YFI5
Ensembl - ENSG00000130038
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CRACR2AENSDARG00000068231Danio rerio
 cracr2abENSDARG00000045758Danio rerio
 Q3UP38ENSMUSG00000061414Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N4Y2 / CRACR2B / calcium release activated channel regulator 2BENSG0000017768517


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR002048  EF-hand domain
 IPR005225  Small GTP-binding protein domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002115 store-operated calcium entry IMP
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0032237 activation of store-operated calcium channel activity IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0051928 positive regulation of calcium ion transport IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0035580 specific granule lumen TAS
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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