ENSG00000130147


Homo sapiens

Features
Gene ID: ENSG00000130147
  
Biological name :SH3BP4
  
Synonyms : Q9P0V3 / SH3BP4 / SH3 domain binding protein 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.2
Gene start: 234951973
Gene end: 235055714
  
Corresponding Affymetrix probe sets: 222258_s_at (Human Genome U133 Plus 2.0 Array)   231468_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000375867
Ensembl peptide - ENSP00000415391
Ensembl peptide - ENSP00000414740
Ensembl peptide - ENSP00000403251
Ensembl peptide - ENSP00000387995
Ensembl peptide - ENSP00000386862
Ensembl peptide - ENSP00000340237
NCBI entrez gene - 23677     See in Manteia.
OMIM - 605611
RefSeq - XM_011510891
RefSeq - XM_011510894
RefSeq - XM_011510893
RefSeq - XM_011510892
RefSeq - NM_014521
RefSeq Peptide - NP_055336
swissprot - Q9P0V3
swissprot - C9JWW6
swissprot - C9JED2
swissprot - C9JF25
swissprot - C9JRG1
Ensembl - ENSG00000130147
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1LVQ2ENSDARG00000020000Danio rerio
 sh3bp4ENSDARG00000030104Danio rerio
 SH3BP4ENSGALG00000004140Gallus gallus
 Q921I6ENSMUSG00000036206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MACC1 / Q6ZN28 / MACC1, MET transcriptional regulatorENSG0000018374237


Protein motifs (from Interpro)
Interpro ID Name
 IPR000906  ZU5 domain
 IPR001452  SH3 domain
 IPR035455  SH3 domain-binding protein 4
 IPR035456  SH3BP4, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0030308 negative regulation of cell growth IMP
 biological_processGO:0032007 negative regulation of TOR signaling IEA
 biological_processGO:0034260 negative regulation of GTPase activity IDA
 biological_processGO:0050790 regulation of catalytic activity IMP
 biological_processGO:0061462 protein localization to lysosome IMP
 biological_processGO:0071230 cellular response to amino acid stimulus IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005092 GDP-dissociation inhibitor activity IMP
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017016 Ras GTPase binding IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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