ENSG00000130517


Homo sapiens

Features
Gene ID: ENSG00000130517
  
Biological name :PGPEP1
  
Synonyms : PGPEP1 / pyroglutamyl-peptidase I / Q9NXJ5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.11
Gene start: 18340587
Gene end: 18369950
  
Corresponding Affymetrix probe sets: 1555165_a_at (Human Genome U133 Plus 2.0 Array)   219891_at (Human Genome U133 Plus 2.0 Array)   223469_at (Human Genome U133 Plus 2.0 Array)   237202_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475867
Ensembl peptide - ENSP00000473772
Ensembl peptide - ENSP00000475477
Ensembl peptide - ENSP00000252813
Ensembl peptide - ENSP00000269919
Ensembl peptide - ENSP00000468932
Ensembl peptide - ENSP00000470622
Ensembl peptide - ENSP00000471130
Ensembl peptide - ENSP00000473226
NCBI entrez gene - 54858     See in Manteia.
OMIM - 610694
RefSeq - XM_017026913
RefSeq - NM_001300927
RefSeq - NM_001308366
RefSeq - NM_001329477
RefSeq - NM_001329478
RefSeq - NM_017712
RefSeq - XM_006722783
RefSeq - XM_011528111
RefSeq - XM_011528112
RefSeq - XM_011528115
RefSeq Peptide - NP_001316406
RefSeq Peptide - NP_001316407
RefSeq Peptide - NP_060182
RefSeq Peptide - NP_001287856
RefSeq Peptide - NP_001295295
swissprot - Q9NXJ5
swissprot - S4R2Y9
swissprot - U3KQ24
swissprot - U3KQG9
swissprot - M0QX66
swissprot - M0R0B6
swissprot - M0R3H3
Ensembl - ENSG00000130517
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGPEP1ENSGALG00000042080Gallus gallus
 Pgpep1ENSMUSG00000056204Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NFU8 / PGPEP1L / pyroglutamyl-peptidase I-likeENSG0000018357137


Protein motifs (from Interpro)
Interpro ID Name
 IPR000816  Peptidase C15, pyroglutamyl peptidase I
 IPR016125  Peptidase C15, pyroglutamyl peptidase I-like
 IPR029761  Pyroglutamyl peptidase I, metazoa
 IPR033693  Pyroglutamyl peptidase I, Glu active site
 IPR033694  Pyroglutamyl peptidase I, Cys active site
 IPR036440  Peptidase C15, pyroglutamyl peptidase I-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016920 pyroglutamyl-peptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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