ENSG00000131375


Homo sapiens

Features
Gene ID: ENSG00000131375
  
Biological name :CAPN7
  
Synonyms : calpain 7 / CAPN7 / Q9Y6W3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.1
Gene start: 15206152
Gene end: 15252918
  
Corresponding Affymetrix probe sets: 203356_at (Human Genome U133 Plus 2.0 Array)   203357_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389786
Ensembl peptide - ENSP00000399486
Ensembl peptide - ENSP00000415482
Ensembl peptide - ENSP00000253693
Ensembl peptide - ENSP00000394708
NCBI entrez gene - 23473     See in Manteia.
OMIM - 606400
RefSeq - XM_017006045
RefSeq - NM_014296
RefSeq - XM_011533555
RefSeq - XM_011533556
RefSeq - XM_011533557
RefSeq - XM_017006043
RefSeq - XM_017006044
RefSeq Peptide - NP_055111
swissprot - F8WDQ3
swissprot - H7C0F1
swissprot - H7C1B7
swissprot - F8WCZ1
swissprot - Q9Y6W3
Ensembl - ENSG00000131375
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capn7ENSDARG00000102987Danio rerio
 CAPN7ENSGALG00000041731Gallus gallus
 Capn7ENSMUSG00000021893Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAPN15 / O75808 / calpain 15ENSG0000010332615
CAPN10 / Q9HC96 / calpain 10ENSG0000014233013


Protein motifs (from Interpro)
Interpro ID Name
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR007330  MIT
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR033883  Calpain subdomain III
 IPR036181  MIT domain superfamily
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IDA
 biological_processGO:0097264 self proteolysis IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004175 endopeptidase activity IDA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0090541 MIT domain binding IPI


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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