ENSG00000131871


Homo sapiens

Features
Gene ID: ENSG00000131871
  
Biological name :SELENOS
  
Synonyms : Q9BQE4 / selenoprotein S / SELENOS
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q26.3
Gene start: 101270817
Gene end: 101277500
  
Corresponding Affymetrix probe sets: 223209_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381282
Ensembl peptide - ENSP00000434842
Ensembl peptide - ENSP00000433803
Ensembl peptide - ENSP00000433541
NCBI entrez gene - 55829     See in Manteia.
OMIM - 607918
RefSeq - NM_018445
RefSeq - NM_203472
RefSeq Peptide - NP_060915
RefSeq Peptide - NP_982298
swissprot - Q9BQE4
swissprot - A0A182DWI4
swissprot - E9PN30
Ensembl - ENSG00000131871
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q0VFV6ENSDARG00000070097Danio rerio
 SELENOSENSGALG00000007162Gallus gallus
 Q9BCZ4ENSMUSG00000075701Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009703  Selenoprotein S


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002865 negative regulation of acute inflammatory response to antigenic stimulus IMP
 biological_processGO:0006111 regulation of gluconeogenesis TAS
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006983 ER overload response IMP
 biological_processGO:0009749 response to glucose IEP
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IDA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IDA
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IDA
 biological_processGO:0032715 negative regulation of interleukin-6 production ISS
 biological_processGO:0032720 negative regulation of tumor necrosis factor production ISS
 biological_processGO:0032869 cellular response to insulin stimulus TAS
 biological_processGO:0034599 cellular response to oxidative stress IMP
 biological_processGO:0045184 establishment of protein localization TAS
 biological_processGO:0045454 cell redox homeostasis IDA
 biological_processGO:0045719 negative regulation of glycogen biosynthetic process TAS
 biological_processGO:0046325 negative regulation of glucose import TAS
 biological_processGO:0050728 negative regulation of inflammatory response IC
 biological_processGO:0051771 negative regulation of nitric-oxide synthase biosynthetic process IMP
 biological_processGO:0051775 response to redox state IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IMP
 biological_processGO:0080164 regulation of nitric oxide metabolic process IMP
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IMP
 biological_processGO:2000110 negative regulation of macrophage apoptotic process IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0034361 very-low-density lipoprotein particle IDA
 cellular_componentGO:0034362 low-density lipoprotein particle IDA
 cellular_componentGO:0036502 Derlin-1-VIMP complex IDA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016209 antioxidant activity IDA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0051117 ATPase binding IPI
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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