ENSG00000135108


Homo sapiens

Features
Gene ID: ENSG00000135108
  
Biological name :FBXO21
  
Synonyms : F-box protein 21 / FBXO21 / O94952
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.22
Gene start: 117141988
Gene end: 117190531
  
Corresponding Affymetrix probe sets: 212229_s_at (Human Genome U133 Plus 2.0 Array)   212231_at (Human Genome U133 Plus 2.0 Array)   214891_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000483508
Ensembl peptide - ENSP00000414468
Ensembl peptide - ENSP00000446973
Ensembl peptide - ENSP00000449264
Ensembl peptide - ENSP00000328187
NCBI entrez gene - 23014     See in Manteia.
OMIM - 609095
RefSeq - XM_017019039
RefSeq - NM_015002
RefSeq - NM_033624
RefSeq - XM_017019037
RefSeq - XM_017019038
RefSeq Peptide - NP_296373
RefSeq Peptide - NP_055817
swissprot - A0A024RBR2
swissprot - H0YHF6
swissprot - H0YIE9
swissprot - A0A024RBL8
swissprot - Q4G104
swissprot - O94952
Ensembl - ENSG00000135108
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxo21ENSDARG00000076611Danio rerio
 FBXO21ENSGALG00000008201Gallus gallus
 Fbxo21ENSMUSG00000032898Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011722  Hemimethylated DNA-binding domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR032698  Protein SirB1, N-terminal
 IPR036047  F-box-like domain superfamily
 IPR036623  Hemimethylated DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process NAS
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0000151 ubiquitin ligase complex NAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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