ENSG00000135413


Homo sapiens

Features
Gene ID: ENSG00000135413
  
Biological name :LACRT
  
Synonyms : lacritin / LACRT / Q9GZZ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.2
Gene start: 54630811
Gene end: 54634895
  
Corresponding Affymetrix probe sets: 224540_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000447536
Ensembl peptide - ENSP00000448193
Ensembl peptide - ENSP00000257867
NCBI entrez gene - 90070     See in Manteia.
OMIM - 607360
RefSeq - NM_033277
RefSeq Peptide - NP_150593
swissprot - Q9GZZ8
swissprot - F8W0V3
swissprot - H0YI00
Ensembl - ENSG00000135413
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR033530  Extracellular glycoprotein lacritin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006473 protein acetylation IMP
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010669 epithelial structure maintenance IDA
 biological_processGO:0016239 positive regulation of macroautophagy IDA
 biological_processGO:0019722 calcium-mediated signaling IDA
 biological_processGO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway IDA
 biological_processGO:0033173 calcineurin-NFAT signaling cascade IDA
 biological_processGO:0034067 protein localization to Golgi apparatus IDA
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050850 positive regulation of calcium-mediated signaling IDA
 biological_processGO:0051047 positive regulation of secretion IDA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA
 biological_processGO:0060054 positive regulation of epithelial cell proliferation involved in wound healing IDA
 biological_processGO:0070075 tear secretion IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0030141 secretory granule IDA
 molecular_functionGO:0001968 fibronectin binding IDA
 molecular_functionGO:0005515 protein binding IDA
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0008083 growth factor activity IDA
 molecular_functionGO:0043237 laminin-1 binding IDA
 molecular_functionGO:0047485 protein N-terminus binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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