ENSG00000135535


Homo sapiens

Features
Gene ID: ENSG00000135535
  
Biological name :CD164
  
Synonyms : CD164 / CD164 molecule / Q04900
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q21
Gene start: 109366514
Gene end: 109382812
  
Corresponding Affymetrix probe sets: 208405_s_at (Human Genome U133 Plus 2.0 Array)   208653_s_at (Human Genome U133 Plus 2.0 Array)   208654_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422999
Ensembl peptide - ENSP00000402237
Ensembl peptide - ENSP00000427546
Ensembl peptide - ENSP00000275080
Ensembl peptide - ENSP00000309376
Ensembl peptide - ENSP00000314177
NCBI entrez gene - 8763     See in Manteia.
OMIM - 603356
RefSeq - NM_001142403
RefSeq - NM_001142401
RefSeq - NM_001142402
RefSeq - NM_001142404
RefSeq - NM_001346500
RefSeq - NM_006016
RefSeq Peptide - NP_006007
RefSeq Peptide - NP_001135873
RefSeq Peptide - NP_001135874
RefSeq Peptide - NP_001135875
RefSeq Peptide - NP_001135876
RefSeq Peptide - NP_001333429
swissprot - Q04900
swissprot - D6R9B4
Ensembl - ENSG00000135535
  
Related genetic diseases (OMIM): 616969 - ?Deafness, autosomal dominant 66, 616969
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd164ENSDARG00000013628Danio rerio
 Cd164ENSMUSG00000019818Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6UWJ8 / CD164L2 / CD164 molecule like 2ENSG0000017495024


Protein motifs (from Interpro)
Interpro ID Name
 IPR007947  CD164-related protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007155 cell adhesion IDA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
 biological_processGO:0007162 negative regulation of cell adhesion NAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0030097 hemopoiesis NAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000006 Autosomal dominant inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele." [HPO:curators]
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 HP:0000407 Hearing loss, sensorineural "Hearing loss caused by damage or dysfunction of the auditory nerve (cranial nerve VIII)." [HPO:curators]
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 HP:0003828 Variable expressivity 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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