ENSG00000135722


Homo sapiens

Features
Gene ID: ENSG00000135722
  
Biological name :FBXL8
  
Synonyms : F-box and leucine rich repeat protein 8 / FBXL8 / Q96CD0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 67159931
Gene end: 67164570
  
Corresponding Affymetrix probe sets: 220080_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427895
Ensembl peptide - ENSP00000464169
Ensembl peptide - ENSP00000430745
Ensembl peptide - ENSP00000430490
Ensembl peptide - ENSP00000430027
Ensembl peptide - ENSP00000429684
Ensembl peptide - ENSP00000428379
Ensembl peptide - ENSP00000258200
NCBI entrez gene - 55336     See in Manteia.
OMIM - 609077
RefSeq - NM_018378
RefSeq Peptide - NP_060848
swissprot - E5RH15
swissprot - E5RFX2
swissprot - J3QRE3
swissprot - E5RIS0
swissprot - Q96CD0
swissprot - E5RIE9
swissprot - E5RHS9
Ensembl - ENSG00000135722
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl8ENSDARG00000054222Danio rerio
 FBXL8ENSGALG00000003201Gallus gallus
 Fbxl8ENSMUSG00000033313Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC074143.1ENSG0000026569039


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr