ENSG00000136146


Homo sapiens

Features
Gene ID: ENSG00000136146
  
Biological name :MED4
  
Synonyms : MED4 / mediator complex subunit 4 / Q9NPJ6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q14.2
Gene start: 48053323
Gene end: 48095131
  
Corresponding Affymetrix probe sets: 217843_s_at (Human Genome U133 Plus 2.0 Array)   222438_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258648
Ensembl peptide - ENSP00000483651
Ensembl peptide - ENSP00000413595
Ensembl peptide - ENSP00000367849
NCBI entrez gene - 29079     See in Manteia.
OMIM - 605718
RefSeq - NM_014166
RefSeq - XM_017020549
RefSeq - NM_001270629
RefSeq Peptide - NP_001257558
RefSeq Peptide - NP_054885
swissprot - A0A024RDY7
swissprot - Q5T911
swissprot - Q9NPJ6
swissprot - A0A087X0U0
Ensembl - ENSG00000136146
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med4ENSDARG00000041503Danio rerio
 MED4ENSGALG00000016995Gallus gallus
 Med4ENSMUSG00000022109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019258  Mediator complex, subunit Med4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IDA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IDA
 biological_processGO:0030521 androgen receptor signaling pathway IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016592 mediator complex IEA
 cellular_componentGO:0070847 core mediator complex IBA
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity NAS
 molecular_functionGO:0042809 vitamin D receptor binding NAS
 molecular_functionGO:0046966 thyroid hormone receptor binding IDA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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