ENSG00000137563


Homo sapiens

Features
Gene ID: ENSG00000137563
  
Biological name :GGH
  
Synonyms : gamma-glutamyl hydrolase / GGH / Q92820
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q12.3
Gene start: 63015079
Gene end: 63039171
  
Corresponding Affymetrix probe sets: 203560_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000260118
NCBI entrez gene - 8836     See in Manteia.
OMIM - 601509
RefSeq - NM_003878
RefSeq - XM_011517623
RefSeq Peptide - NP_003869
swissprot - Q92820
Ensembl - ENSG00000137563
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gghENSDARG00000037176Danio rerio
 GGHENSGALG00000031130Gallus gallus
 GghENSMUSG00000073987Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011697  Peptidase C26
 IPR015527  Peptidase C26, gamma-glutamyl hydrolase
 IPR029062  Class I glutamine amidotransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010043 response to zinc ion IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0046900 tetrahydrofolylpolyglutamate metabolic process IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005773 vacuole IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904724 tertiary granule lumen TAS
 molecular_functionGO:0008238 exopeptidase activity TAS
 molecular_functionGO:0008242 omega peptidase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0034722 gamma-glutamyl-peptidase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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