ENSG00000138092


Homo sapiens

Features
Gene ID: ENSG00000138092
  
Biological name :CENPO
  
Synonyms : CENPO / centromere protein O / Q9BU64
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p23.3
Gene start: 24793136
Gene end: 24822376
  
Corresponding Affymetrix probe sets: 219472_at (Human Genome U133 Plus 2.0 Array)   226118_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000260662
Ensembl peptide - ENSP00000370214
Ensembl peptide - ENSP00000417787
NCBI entrez gene - 79172     See in Manteia.
OMIM - 611504
RefSeq - NM_001322101
RefSeq - NM_001199803
RefSeq - NM_024322
RefSeq Peptide - NP_001186732
RefSeq Peptide - NP_001309030
RefSeq Peptide - NP_077298
swissprot - Q9BU64
Ensembl - ENSG00000138092
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cenpoENSDARG00000075619Danio rerio
 CENPOENSGALG00000016609Gallus gallus
 CenpoENSMUSG00000020652Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018464  Centromere protein O


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0034080 CENP-A containing nucleosome assembly TAS
 biological_processGO:0034508 centromere complex assembly IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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